Rheumatoid arthritis (RA) is a chronic autoimmune disorder that can affect anyone regardless of age, gender, or ethnicity. People with RA experience inflammation of their joints, leading to symptoms such as pain, stiffness, and fatigue. RA occurs when the body's immune system mistakenly attacks its own joints, causing them to become swollen and painful.

Genetics plays a major role

There are several factors that can increase a person’s risk of developing RA. Genetics plays a role; a person whose parent or sibling has RA is three to five times more likely to create it. Other risk factors include age and smoking; RA is more likely to affect people over 40, and smoking has been linked to an increased risk of developing the disorder. Women are also more likely to develop RA than men; some studies have found that as many as three times as many women as men have RA.

Lifestyle choices can make an individual vulnerable

No one is immune to RA, and anyone can become a victim of the disorder. Environmental factors, such as environmental pollutants, can also contribute to a person’s risk of developing the condition. In addition, lifestyle choices, such as an unhealthy diet, can increase the risk of developing RA. Additionally, certain infections, such as Epstein-Barr virus and rubella, can contribute to an individual’s risk of developing RA.

Symptoms tend to begin and fluctuate gradually

RA is hard to diagnose as symptoms are often similar to other medical conditions. Symptoms generally begin gradually and can vary from person to person. These can include swollen and painful joints, loss of joint function, fatigue, and even fever. Early diagnosis is key to successful treatment, so it’s important to see a doctor if you experience any of these symptoms.

Treatment based systems

Treatment for RA can range from lifestyle modifications, such as reducing stress and getting enough sleep, to medication and surgical options. Non-steroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and disease-modifying anti-rheumatic drugs (DMARDs) are typically used to reduce inflammation and help alleviate the symptoms of RA. In some cases, surgery may be necessary to repair or replace a damaged joint.

 Rheumatoid arthritis affects in India

Rheumatoid arthritis often referred to as RA, is an autoimmune disease in which the body's immune system attacks its own healthy tissue in the joints. In India, it is estimated that 2.1% of the population over the age of 15 suffers from RA. This can lead to countless complications that can severely impact one's life and well-being.

This puts them at risk of other bone-related issues

The most common effects of RA in India are widespread pain, especially in the joints and other areas such as the feet and hands. This pain may increase over time depending on the severity and can be accompanied by stiffness and swelling in the joints, which makes them tender to the touch and may eventually lead to deformities in severe cases. Those who suffer from RA are at risk of developing other diseases, such as osteoporosis, given the loss of bone density that may occur over time. Moreover, due to the chronic pain, fatigue, and stiffness associated with the disease, those who suffer from it may experience anxiety, depression, or other mental health concerns.

Consistent and well-developed medical care is required

When it comes to treatment and prevention, RA is a serious condition that requires consistent and ongoing medical care. Currently, India has several public and private health services to address the condition, however, many struggle to access proper care due to economic, social, or geographic barriers. Those with the disease may find it difficult to access proper medication or specialized resources to help manage pain and other symptoms.

Ayurvedic formulations as a fast formulation

In some cases, traditional Indian medicine such as Ayurveda is used to treat RA. This can be beneficial as Ayurvedic medicine focuses on both targeting the symptom and the root cause of the disease. However, it is important to ensure that any traditional method is used under the supervision of a qualified health provider and in conjunction with a prescribed drug regimen.

Impact of RA

Ultimately, RA can impact people of any age and socio-economic background. Therefore, it is important that more awareness and resources are available to those who suffer from this condition in India. This includes increased access to medical services and guides, as well as resources that help lift the stigma associated with the disease, promote early diagnosis, support those struggling with pain management, and provide a supportive community.

Managing the condition

Xeljanz (tofacitinib) tablets are an effective oral medication used to treat adults with moderate to severe rheumatoid arthritis (RA). Prescribed by healthcare professionals, Xeljanz tablets make it easier for people to manage their conditions by helping reduce joint pain and swelling, reducing physical disability, and improving overall physical function.

Inhibitor of Janus kinase inhibitor

Xeljanz is a Janus Kinase (JAK) inhibitor, which binds to the non-functioning JAK3 enzymes found in patients with rheumatoid arthritis. By doing this, Xeljanz helps to restore proper function to the JAK enzymes, which helps to reduce the symptoms of RA. This mechanism of action makes Xeljanz an effective form of treatment that can help provide pain relief and improve physical function in RA patients.

The combined form of therapy

Tab Xeljanz 5m uses alone or in combination with methotrexate, which is a common drug used to treat RA. Depending on the level of symptom relief desired, a healthcare provider may adjust the dose or frequency of Xeljanz use. This flexibility is beneficial to patients seeking individualized and tailored treatment options.

Preventing RA reoccurrence

In addition to relieving symptoms of RA, one of the many benefits of Xeljanz is that it can also help prevent RA flare-ups. This is due to its ability to not only reduce current signs and symptoms but also reduce the risk for future disease activity. Xeljanz can also help prevent and slow the progression of joint damage, which can help improve overall physical function and quality of life.

Effects to be taken with care

Patients taking Xeljanz should discuss potential risks and side effects with their healthcare provider prior to starting the medication, as some people may experience itching, an increased risk of infection, or an increased risk of lymphoma.


Overall, Xeljanz (tofacitinib) tablets are an effective oral medication prescribed for the treatment of adults with moderate to severe rheumatoid arthritis. By restoring proper function to the non-functioning JAK3 enzymes, Xeljanz works to reduce the joint pain, physical disability, and swelling associated with RA, while also helping prevent future flare-ups and slowing down the progression of joint damage. Patients taking Xeljanz should discuss potential risks and side effects with a healthcare provider prior to starting the medication.


It’s important to remember that anyone can be a victim of rheumatoid arthritis. The disorder can affect individuals of any age, gender, ethnicity, or background, so it’s important to be aware of the symptoms and risk factors. If you experience any of the symptoms of RA, then it’s important to seek medical attention as soon as possible. With early diagnosis and a combination of treatment options, it is possible to manage RA and lead a full and active life.

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